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2013년 11월 30일 토요일

Does smoking have an impact on fusion rate in single-level anterior cervical discectomy and fusion with allograft and rigid plate fixation?

Brief review

이 논문은 단일분절에 전방경유 경추 절제 및 유합술(ACDF)를 시행한 환자들을 대상으로 흡연여부가 유합률에 영향을 주는가에 대해 연구한 내용 입니다.

단일 분절에 ACDF를 시행한 환자 573(흡연자156+비 흡연자417)의 데이터를 분석하여 수술시점으로부터 2년이 지난 후, 방사선학적 측정을 통해 유합률을 조사하였습니다
.
결과적으로 본 연구의 대상이 된 흡연, 비 흡연 환자들 간의 유합률에는 통계적으로 유의한 차이가 없다고 합니다. (p=0.867)



*Title: Does smoking have an impact on fusion rate in single-level anterior cervical discectomy and fusion with allograft and rigid plate fixation?
흡연이 동종골과 금속판 고정을 동반한 전방경유 경추 절제 및 유합술에서 유합률에 영향을 미치는가?

*Authors: Myles Luszczyk, Justin S. Smith, Jeffrey S. Fischgrund, Steven C. Ludwig, Rick C. Sasso, Christop her I. Shaffrey, Alexander R. Vaccaro




Object
Effect of smoking on fusion rates of the cervical and lumbar spine
: -In multilevel fusions: shown to negatively affect. (in cervical and lumbar)
-In single-level anterior cervical discectomy and fusion(ACDF): has yet to investigated.

Purpose: To address the effect of smoking on fusion rates in patients undergoing a 1-level ACDF with allograft and a locked anterior cervical plate.


Methods
Subject: patients underwent a 1-level ACDF with allograft and a locked cervical plate.

Subject number: 573 patients(156 smokers + 417 nonsmokers)

follow-up period: 24 months

Evaluation method: assessed radiographic evidence (lateral, neutral, and flexion/extension)

-The authors reviewed subject patients data.


Results
Overall fusion rate: 91.4% (all patients)

Solid fusion:
- nonsmokers: 382 patients (91.6%)
- smokers: 142 (91.0%)
-->No difference in the union rates between smokers and nonsmokers.(p=0.867)


Conclusions
Not significantly different in fusion status between smokers and nonsmokers who underwent a single-level ACDF with allograft and a locked anterior cervical plate.